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Mutations identified in patients with defective lipoic acid metabolism affect genes involved in the synthesis of iron-sulfur clusters and genes coding for lipoic acid synthetase ( LIAS ), lipoyl transferase 1 ( LIPT1 ), and dihydrolipoamide dehydrogenase (E3 component of -ketoacid dehydrogenase complexes
Dettman EJ, Doykan C, Cardone MH, Hills R, White P, Burnett AK, Andreeff M
Glutathione enables the detoxification process of the body
Repeated freeze-thaw cycles should be avoided when possible, as each cycle can cause incremental loss of activity through partial aggregation
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